What are the uses of refrigerated air dryer? How to choose one?

In the vast field of scientific research experiments, refrigerated air dryer technology is like a bright pearl, emitting irreplaceable light, especially in many important fields related to people’s livelihood and scientific development, such as biological products, drugs, and food. It has become an indispensable key link in preservation and research work. Choosing a freeze dryer that meets your needs is like equipping a scientific research experiment with a precise blade. It can not only significantly improve the efficiency of the experiment, but also accelerate the experimental process. It can also be like a solid foundation to ensure the accuracy and reliability of the experimental results and lay a solid foundation for the birth of scientific research results.

As a professional leader in the field of laboratory instruments, Southeast Yicheng sincerely leads you to explore in depth, based on your unique experimental needs, complex and diverse application scenarios and other key factors, to fully and accurately understand how to choose the most suitable freeze dryer for you, to escort your scientific research.

1. Working principle
As a precision instrument that uses advanced technology to dry items, the working principle of the freeze dryer contains scientific subtleties. It first places the water-containing items in a specific low-temperature environment, and through precise temperature control, the water in the items is quickly frozen into solid ice crystals. This process is like freezing time and locking the water firmly in a solid frame. Then, in a vacuum state, the ice crystals directly sublimate into water vapor, detach from the object, and finally obtain a dry object. This magical process is like a magic show in the microscopic world. It not only keeps the physical and chemical properties and biological characteristics of the object basically unchanged, as if it were cast with a protective spell, but also makes it easy to preserve for a long time, as if opening a time safe for the object. When needed, the rehydrated objects can quickly return to their pre-freeze-dried form, like a sleeping elf waking up, and can perfectly maintain their original biochemical characteristics, providing a reliable material basis for subsequent research and application.
2. Application scenarios
Drug research and development
In the long journey of drug research and development, refrigerated air dryer technology is like a capable assistant, playing a pivotal role. It can be used to prepare dry dosage forms of drugs, among which freeze-dried powder injection is its outstanding representative work. This dosage form is like a solid armor for drugs, with excellent characteristics of good stability, which can effectively resist interference from the external environment and ensure that the drug remains active during storage. At the same time, its advantages of easy storage and transportation enable drugs to cross thousands of mountains and rivers and quickly reach where they are needed, bringing hope to patients. For example, in the research and development of some anti-cancer drugs, freeze-dried powder injections not only help improve the efficacy of drugs, as if injecting powerful energy into the drugs, but also reduce side effects and alleviate the pain of patients during treatment, making important contributions to the development of the medical industry.
Biological sample preservation
For the preservation of biological samples, refrigerated air dryer technology is undoubtedly a magical key that can open the door to long-term storage and convenient transportation of samples. Whether it is precious cells, complex tissues, or tiny microorganisms and other biological samples, through the magic of refrigerated air dryer, they can be safely preserved for a long time without any damage to their structure and activity. This is like finding a permanent safe haven for biological samples, allowing them to be safe and sound in the long river of time. Moreover, the convenient transportation characteristics enable these samples to be smoothly transferred between different laboratories, building a solid bridge for scientific research cooperation around the world, providing a reliable source of samples for subsequent experimental research, and helping researchers explore the mysteries of life.
Materials Science Research
In the frontier of materials science research, refrigerated air dryer technology is like an innovative artist who can create amazing new materials. It can be used to prepare porous materials, nanomaterials and other materials with unique properties. By carefully optimizing the refrigerated air dryer process and conditions, researchers seem to have a pair of magical hands that can accurately regulate the structure and properties of materials. For example, in the biomedical field, porous materials prepared by refrigerated air dryer technology can be used as scaffolds for cell growth, providing new possibilities for the development of tissue engineering; while nanomaterials show great potential in drug delivery, biosensing and other aspects. This precise control of material properties will help expand its application range in multiple fields and promote the continuous development of materials science.
3. How to select a freeze dryer
Choice of glass cover
The choice of glass cover is like choosing a suitable coat for the freeze dryer, which needs to be accurately judged according to the specific experimental requirements. If the experiment requires the capping of the vial, just like putting a delicate hat on the bottle, then the capping glass cover is the best choice. It can perfectly adapt to the capping operation to ensure the smooth progress of the experiment. If you need to take out the sample for separate observation during the vacuuming process, just like taking out treasures from a mysterious treasure box and carefully examining them, the manifold glass cover can meet this demand and provide a convenient operation method for the experimenter. For general samples, you only need to simply put them on the tray for vacuuming, and the ordinary glass cover can do the job, providing basic guarantee for the experiment with its simple and practical characteristics.
Water Capture Capacity
The water capture capacity is the amount of water that the freeze dryer can evaporate within 24 hours. This parameter is like the “appetite” size of the freeze dryer. Different experimental needs have different requirements for water evaporation. For example, in large-scale biological sample refrigerated air dryer experiments, a large amount of water needs to be processed. At this time, it is necessary to choose a freeze dryer with strong water capture capacity to ensure that the drying task can be completed efficiently. For some small experiments, equipment with moderate water capture capacity can meet the needs and avoid waste of resources.
Cold Trap Temperature
When there are pre-frozen samples and they need to be further frozen in the cold trap, the cold trap temperature becomes a key factor. This is like choosing a suitable “refrigerator” temperature for the sample. Different samples have specific requirements for freezing temperature. For example, some biological samples need to be kept at extremely low temperatures to maintain their activity and structural integrity. This requires the accurate selection of the cold trap temperature of the freeze dryer according to the freezing temperature required by the sample to ensure that the sample is best protected during the refrigerated air dryer process.
Ultimate vacuum degree

The ultimate vacuum degree is generally ≤10pa. This indicator is like creating an extreme vacuum environment for the freeze dryer. In this nearly perfect vacuum world, water can sublimate more smoothly, thereby improving drying efficiency and quality. For some experiments with extremely high vacuum requirements, such as the preparation of some high-end materials, it is very important to choose a freeze dryer with an ultimate vacuum degree that meets the requirements, which can ensure the accuracy and reliability of the experimental results.
Vacuum pump
The vacuum pump is one of the core components of the freeze dryer, and the standard configuration is usually a domestic pump. Domestic pumps can meet the needs of most conventional experiments with their high cost-effectiveness and stable performance. However, for some scientific research projects with more stringent requirements on vacuum performance and extremely high experimental accuracy, imported pumps can also be selected. Imported pumps often have unique advantages in technology and performance, and can provide a more stable and efficient vacuum environment, providing strong support for high-end experiments.
4. Use of freeze dryer
Before starting the machine each time, just like checking the equipment before starting an important journey, first carefully check whether there is enough pump oil in the vacuum pump. Pump oil is like the blood of the vacuum pump. Adequate pump oil can ensure the normal operation of the vacuum pump and provide stable power support for the entire refrigerated air dryer process.
Unscrew the drain valve to let the remaining water flow out. This step is like draining the “waste water” from the freeze dryer. After draining, tighten the valve to ensure that the internal environment of the equipment is clean and dry, and prepare for subsequent work.
Check whether the contact part between the refrigerated air dryer chamber and the cold trap is intact, which is like checking whether the connection between the two important components is tight. Clean and readjust if necessary to ensure that the refrigerated air dryer chamber and the cold trap are well sealed to avoid air leakage during the vacuum process and affect the drying effect.

Close all valves, and the valve directly connected to the refrigerated air dryer bottle is closed when the white knob is turned up. At the same time, close the valve connecting the cold trap to the vacuum pump. This valve is located behind the instrument and connected to the vacuum tube. This step is like setting up a safety barrier for the refrigerated air dryer process to ensure that there will be no unexpected gas circulation during the preparation stage.
Turning on the cold trap power switch and the vacuum pump power switch is like starting the two core engines of the freeze dryer. Let them start running and warm up for the subsequent work.
After 15 minutes, open the valve connecting the cold trap and the vacuum pump, which is like opening a channel connecting two important areas, so that a vacuum environment can be formed in the entire system.
After 1 minute, the pre-frozen samples, which are already in the freeze-dried bottles, can be hung on the bracket, and the refrigerated air dryer process can be carried out after opening the corresponding valve. This step is like putting the prepared “raw materials” into the production line and starting the magical journey of refrigerated air dryer.
After the refrigerated air dryer is completed, close the corresponding valve, turn the white knob upward, and remove the freeze-dried bottle. This is like completing a production task, closing the production line, and taking out the finished product.
After all the freeze-dried bottles are removed, turn off the vacuum pump power and the cold trap power in turn, just like drawing a perfect end to this refrigerated air dryer journey.
After the frost in the cold trap melts, open the drain valve to drain, and then close it. This step is like cleaning up the battlefield after the journey, ensuring that the equipment can meet the next task in good condition.
V. Precautions
The sample must be pre-frozen before refrigerated air dryer, which is like putting on a layer of “freezing armor” for the sample. The sample must be in a solid state, that is, in an ice state, before it can be freeze-dried, and the longer the pre-freezing time, the better the refrigerated air dryer effect. At the same time, the volume of the sample should not exceed 1/3 of the volume of the sample bottle, which is like reserving enough space for the sample in the bottle to ensure the smooth progress of the refrigerated air dryer process.
If the sample melts during refrigerated air dryer, and the vacuum pump and cold trap are in good working condition, the reason is probably that the vacuum is not enough and there is a leak. At this time, you need to check carefully like a detective whether all valves are closed, whether the contact between the refrigerated air dryer chamber and the cold trap surface is sealed, and clean the cold trap surface and the sealing ring of the refrigerated air dryer chamber when necessary to ensure that the entire system is well sealed.
Regularly cleaning the cold trap chamber and the refrigerated air dryer chamber is like regularly cleaning the room, keeping the inside of the equipment clean and hygienic, which helps to improve the working efficiency and service life of the equipment.
refrigerated air dryer can be done 15 minutes after starting up, the purpose is to pre-cool the cold trap and preheat the vacuum pump. This is like an athlete doing warm-up exercises before a game, so that the instrument can work in the best working condition and ensure the accuracy and stability of the experimental results.
After the refrigerated air dryer is completed and the valve is closed, the inside of the freeze-dried bottle is connected to the outside world, and the bottle can be removed after the air pressure is balanced. This is like waiting for a safety signal to ensure that the sample is taken out safely to avoid damage to the sample due to air pressure difference.
Clean the dust inside the compression bottle regularly, and refuel the vacuum pump when the oil is low. This is like regular maintenance and maintenance of the equipment to ensure that the equipment is always in good operating condition and provide reliable support for scientific research experiments.
Southeast Yicheng has always adhered to the concept of providing all-round services to scientific researchers. It will gradually organize practical information such as installation instructions, user guides, maintenance and repair methods of various laboratory instruments and equipment, hoping to be like a bright lighthouse, illuminating the way forward for laboratory managers, scientific instrument sales, instrument technical service personnel and other related personnel, and helping the scientific research cause to flourish.